Chicago Tribune reporter Melissa Isaacson explores Piniella's background, his parents, friends, and roots in Tampa that explain his famous hot-headedness and reveal a down-to-earth family man. Along the way, she chronicles Piniella's ascension to become the beloved skipper of the Chicago Cubs who immediately set his sights on his sixth pennant and the possibility of leading the Cubs to a world championship.

Isaacson also examines Piniella's life outside of baseball, revealing a multifaceted and highly active businessman. A chapter devoted to the famous temper relives some of the stories that have made him the bane of umpires around both leagues. Sweet Lou is a riveting and enjoyable portrayal of a consummate competitor and controversial larger-than-life baseball personality whose full impact on the game has yet to be measured.