The Condition tells the story of a proper New England family that comes apart one fateful summer. To their dismay, Frank and Paulette McKotch's daughter, Gwen, has been diagnosed with Turner's syndrome—a genetic condition that leaves her trapped forever in the body of a child, and sparks heated dispute between the couple.

Twenty years later, their three children—now grown, and each struggling with secret conditions of their own—are still dealing with the fallout of Frank and Paulette's divorce. Then, suddenly, Gwen falls in love for the first time, and the family's world is again tilted on its axis.

In an era when individual quirks look increasingly like symptoms and every symptom demands to be treated, the McKotches are determined to fix themselves and each other. They are a family for our time.