In the first US novelization of Blood+ we find Saya Otonoshi, a high shcool student, suffering from amneisa. Saya can't remember anything from her life beyond the last year. Living with a foster family outside a military base in Okinawa, Japan, Saya's attempts to live a normal life are shattered when a Chiropteran, a horrific vampire-like monster, attacks her. Saved at the last minute by a mysterious man named Hagi, Saya is presented with a sword that awakens in her a warrior's skills and bloodlust, and sets her on a course that will lead her to the answers of her missing memories, and into battle against a race of creatures intent on destroying the world. The epic adventure that began in the groundbreaking film Blood: The Last Vampire and continued through the worldwide phenomenon TV series Blood+ is brought to life in this all-new series of novels adapting the hit show. Saya's journey of horror, magic, romance and mystery will stretch across time and around the world, expanding on the television series with new characters, new adventures, and breathtaking action....

Following the traces of Diva, the leader of the Chiroptera, Saya and her group make their way to Russia. But awaiting their arrival is Diva's powerful protector Chiroptera, "The Chevalier." In the middle of the battle against this new threat, Saya is told a horrible truth - "It is because you are one of us." Is Saya a human, or something more sinister... ?...

In her attempts to stop Diva's plan of turning all of mankind into Chiropterans, Saya makes her way to the United States. Despite her forced rest, the time for action draws near. Meanwhile, Diva, carrying Riku's children, makes preparations for the birth of the queens of the next generation! With the fate of humanity resting with the two queens, who will rise and who will fall in the final showdown?! And what of the "promise" Saya made with Haji?...