The speculation that the United States did infect Indian populations has long been a source of both outrage and skepticism. Now there is an exhaustively researched exploration of an issue that continues to haunt U.S.-Native American relations.

Barbara Alice Mann's The Tainted Gift: The Disease Method of Frontier Expansion offers riveting accounts of four specific incidents: The 1763 smallpox epidemic among native peoples in Ohio during the French and Indian War; the cholera epidemic during the 1832 Choctaw removal; the 1837 outbreak of smallpox among the high plains peoples; and the alleged 1847 poisonings of the Cayuses in Oregon. Drawing on previously unavailable sources, Mann's work is the first to give one of the most controversial questions in U.S. history the rigorous scrutiny it requires.

The Revolutionary War is ordinarily presented as a conflict exclusively between colonists and the British, fought along the northern Atlantic seacoast. This important work recounts the tragic events on the forgotten Western front of the American Revolution—a war fought against and ultimately won by Native America. The Natives, primarily the Iroquois League and the Ohio Union, are erroneously presented in history texts as allies (or lackeys) of the British, but Native America was working from its own internally generated agenda: to prevent settlers from invading the Old Northwest. Native America won the war in the West, holding the land west and north of the Allegheny-Ohio River systems. While the British may have awarded these lands to the colonists in the Treaty of Paris, the Native Americans did not concur.

Throughout the war, the unwavering goal of the Revolutionary Army, under George Washington, and their associated settler militias was to break the power of the Iroquois League, which had successfully held off invasion for the preceding two centuries, and the newly formed Ohio Union. To destroy the Natives in the way of land seizure, Washington authorized a series of rampages intended to destroy the League and the Union by starvation. Food, livestock, homes, and trees were destroyed, first in the New York breadbaskets, then in the Ohio granaries—spreading famine across Native lands. Uncounted thousands of Natives perished from New York to Pennsylvania to Ohio. This book tells how, in the wake of the massive assaults, the Natives held back the American onslaught.